Walsh R M, Bath A P, Bance M L
Department of Otolaryngology, University Health Network, Toronto General Hospital, University of Toronto, Canada.
ORL J Otorhinolaryngol Relat Spec. 2000 May-Jun;62(3):156-9. doi: 10.1159/000027737.
We report an unusual case of tobramycin-induced bilateral high-frequency vestibular toxicity with subsequent clinical and objective evidence of functional recovery. In those patients with a clinical presentation suggestive of aminoglycoside-induced bilateral vestibular toxicity (ataxia and oscillopsia) and normal low-frequency (ENG-caloric) responses, high-frequency rotation chair testing should be performed to exclude a high-frequency vestibular deficit.
我们报告了一例罕见的妥布霉素诱发双侧高频前庭毒性并随后出现功能恢复的临床及客观证据的病例。对于那些临床表现提示氨基糖苷类药物诱发双侧前庭毒性（共济失调和视振荡）且低频（眼震电图-冷热试验）反应正常的患者，应进行高频转椅试验以排除高频前庭功能缺陷。
