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一次和三次注射可的松或甲状腺素对乳鼠肠道乳糖酶活性的相反作用。

Opposite effects of one and three injections of cortisone or thyroxine on intestinal lactase activity in suckling mice.

作者信息

Malo C, Ménard D

出版信息

Experientia. 1979 Apr 15;35(4):493-4. doi: 10.1007/BF01922726.

DOI:10.1007/BF01922726
PMID:108133
Abstract

A single injection of cortisone or thyroxine to 8-day-old suckling mice initiates a temporary decrease of lactase activity. On the contrary, 3 injections of cortisone or thyroxine provoke a significant increase of lactase activity. It appears that the mechanism which controls the postnatal development of lactase in suckling animals is more complex than expected.

摘要

对8日龄的哺乳小鼠单次注射可的松或甲状腺素会引发乳糖酶活性的暂时下降。相反,注射3次可的松或甲状腺素会使乳糖酶活性显著增加。看来,控制哺乳动物出生后乳糖酶发育的机制比预期的更为复杂。

相似文献

1
Opposite effects of one and three injections of cortisone or thyroxine on intestinal lactase activity in suckling mice.一次和三次注射可的松或甲状腺素对乳鼠肠道乳糖酶活性的相反作用。
Experientia. 1979 Apr 15;35(4):493-4. doi: 10.1007/BF01922726.
2
Insulin-evoked precocious appearance of intestinal sucrase activity in suckling mice.
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4
Hormonal control of postnatal development of ileal neuraminidase and acid beta-galactosidase.
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Cortisone and thyroxine modulate intestinal lactase and sucrase mRNA levels and activities in the suckling rat.可的松和甲状腺素可调节乳鼠肠道乳糖酶和蔗糖酶的mRNA水平及活性。
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Lactase activity is under hormonal control in the intestine of adult rat.乳糖酶活性在成年大鼠肠道中受激素控制。
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Lactase enzymes in the intestinal brush border membrane of the suckling rat. A second enzyme restricted to ileum.
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Effects of cortisone and thyroxine on suckling rat liver N-acetyl-beta-glucosaminidase isozymes. Comparison with adult reactivity.可的松和甲状腺素对乳鼠肝脏N-乙酰-β-氨基葡萄糖苷酶同工酶的影响。与成年鼠反应性的比较。
Biochim Biophys Acta. 1980 Jun 19;630(2):279-86. doi: 10.1016/0304-4165(80)90432-8.

引用本文的文献

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Organ culture of suckling rat intestine: comparative study of various hormones on brush border enzymes.乳鼠肠道器官培养:多种激素对刷状缘酶的比较研究
In Vitro. 1982 Apr;18(4):339-46. doi: 10.1007/BF02796332.
2
Susceptibility of mice to rotavirus infection: effects of age and administration of corticosteroids.小鼠对轮状病毒感染的易感性:年龄及皮质类固醇给药的影响
Infect Immun. 1981 Aug;33(2):565-74. doi: 10.1128/iai.33.2.565-574.1981.
3
Reversibility of spermine-induced intestinal maturation in the rat.精胺诱导的大鼠肠道成熟的可逆性

本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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Effect of cortisone on the developmental pattern of the neutral and the acid beta-galactosidase of the small intestine of the rat.可的松对大鼠小肠中性和酸性β-半乳糖苷酶发育模式的影响。
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Intestinal lactase activity in the suckling rat: influence of hypophysectomy and thyroidectomy.乳鼠肠道乳糖酶活性:垂体切除和甲状腺切除的影响。
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8
Disaccharidases in the small intestine of the mouse: normal development and influence of cortisone, actinomycin D, and cycloheximide.小鼠小肠中的双糖酶:正常发育以及可的松、放线菌素D和环己酰亚胺的影响。
Dev Biol. 1973 Nov;35(1):143-59. doi: 10.1016/0012-1606(73)90012-2.
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Development of intestinal function in mammals.哺乳动物肠道功能的发育
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Studies on normal and precocious appearance of jejunal sucrase in suckling rats.乳鼠空肠蔗糖酶正常及早熟出现的研究。
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