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用于确定受干扰的集体埋葬遗址中亲属关系的古DNA分型方法。

Ancient DNA-typing approaches for the determination of kinship in a disturbed collective burial site.

作者信息

Schultes T, Hummel S, Herrmann B

机构信息

Institute of Zoology and Anthropology, University of Göttingen.

出版信息

Anthropol Anz. 2000 Mar;58(1):37-44.

Abstract

Several DNA-typing approaches are applied for identification and kinship analysis. Autosomal Short Tandem Repeat (STR) typing produces the genetic fingerprint that is unique to an individual. Y-chromosomal STR typing identifies individuals of the same paternal lineage, and sequence analysis of the hypervariable region of the mitochondrion can identify maternally related individuals. The combined approach of these DNA-typing methods allows the determination of kinship even in complex collective burial situations. In a bronze age collective site, the typing methods were tested for applicability to ancient DNA. For each approach, results were obtained, leading to the conclusion that the determination of kinship is achievable.

摘要

几种DNA分型方法被应用于身份鉴定和亲属关系分析。常染色体短串联重复序列(STR)分型产生个体独特的基因指纹。Y染色体STR分型可识别同一父系血统的个体,线粒体高变区的序列分析可识别母系相关个体。这些DNA分型方法的联合应用甚至在复杂的集体埋葬情况下也能确定亲属关系。在一个青铜时代的集体遗址,测试了这些分型方法对古代DNA的适用性。对于每种方法,都获得了结果,得出了亲属关系是可以确定的结论。

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