Hummel S, Herrmann B
Institut für Anthropologie, Universität Göttingen.
Anthropol Anz. 1997 Jun;55(2):217-23.
Molecular sex determination and aDNA typings were carried out on a group of five prehistoric individuals. Due to the burial situation and the individual ages the group was assumed to be a family consisting of the parents and three children. DNA was extracted from teeth and bone samples of all skeletons. The aDNA typings based on the PCR amplification of four different microsatellite DNA loci, so-called human short tandem repeats (STR). Results of the molecular sex determinations and allele determinations are presented and compared with morphological determinations. Up to now, the individual biological kinship could be verified for three of the individuals. This is the first proof of individual biological kinship on the molecular level for prehistoric individuals.
对一组五名史前个体进行了分子性别鉴定和古DNA分型。由于埋葬情况和个体年龄，该组被假定为一个由父母和三个孩子组成的家庭。从所有骨骼的牙齿和骨骼样本中提取了DNA。基于四个不同微卫星DNA位点（即所谓的人类短串联重复序列，STR）的PCR扩增进行古DNA分型。给出了分子性别鉴定和等位基因鉴定的结果，并与形态学鉴定结果进行了比较。到目前为止，已在分子水平上验证了其中三名个体之间的生物学亲缘关系。这是史前个体在分子水平上存在生物学亲缘关系的首个证据。
