Mackenzie I F, Buckingham K, Wankowski J M, Wilcock M
Cornwall and Isles of Scilly Health Authority.
Br J Gen Pract. 1999 Nov;49(448):884-6.
Although the link between depression, unemployment, and measures of deprivation and morbidity has been previously documented, the relationship between general practice prescribing of antidepressants, morbidity, and the social demography of general practice populations is poorly understood.
To consider whether morbidity and the social demography of general practice populations influence the prescribing costs of individual practices.
Data were analysed, using a forward stepwise regression procedure, of all 78 practices served by the Cornwall and Isles of Scilly Health Authority. Data on prescribing for antidepressants were provided by the Prescription Pricing Authority for the period from July to December 1995 and converted into defined daily doses (DDDs) to standardize for the variation in prescribing practice between general practitioners.
A significant positive correlation exists between the rates of prescribing DDDs of antidepressants by general practices and the prevalence of permanent sickness in the areas in which these practices serve.
Demonstrating an association between morbidity and prescribing rates for depression may prove helpful in setting prescribing budgets.
尽管抑郁症、失业以及贫困与发病率之间的联系此前已有文献记载，但对抗抑郁药物在全科医疗中的处方开具情况、发病率以及全科医疗人群的社会人口统计学之间的关系却了解甚少。
探讨全科医疗人群的发病率和社会人口统计学特征是否会影响个体诊所的处方成本。
使用向前逐步回归程序，对康沃尔郡和锡利群岛卫生局服务的所有78家诊所的数据进行分析。抗抑郁药物的处方数据由处方定价机构提供，时间为1995年7月至12月，并转换为限定日剂量（DDD），以标准化全科医生之间处方习惯的差异。
全科诊所开具抗抑郁药物DDD的比率与这些诊所所服务地区的长期疾病患病率之间存在显著正相关。
证明发病率与抑郁症处方率之间的关联可能有助于制定处方预算。
