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不同教育群体中精神药物使用模式及相关疾病:全国横断面调查

Patterns of psychotropic medicine use and related diseases across educational groups: national cross-sectional survey.

作者信息

Nielsen Merete W, Hansen Ebba Holme, Rasmussen Niels Kristian

机构信息

Department of Social Pharmacy, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, 2100 Copenhagen, Denmark.

出版信息

Eur J Clin Pharmacol. 2004 May;60(3):199-204. doi: 10.1007/s00228-004-0741-4. Epub 2004 Mar 16.

Abstract

OBJECTIVE

To analyse whether the use of different groups of psychotropic medicines among educational groups in a general population was congruent with the occurrence of related diseases.

METHODS

Data from The Danish Health and Morbidity Survey 2000 were analysed. The survey was conducted by face-to-face interviews with a representative sample of the Danish population aged 16 years and above ( n=16,690). The prevalence of four different types of psychotropic medicine use and related diseases in educational groups was analysed by indirect standardisation. Age and gender standardised prevalence ratios (SPRs) and 95% confidence intervals were calculated based on the total study population.

RESULTS

In general, respondents in the two least-educated groups used psychotropic medicines more often and had a higher proportion reporting the related disease than could be expected according to indirect standardisation. The opposite picture appeared for respondents in the two highest educated groups (SPR<100). The overall patterns were similar for all four groups of psychotropic medicine users, although some of the SPRs were not significant.

CONCLUSIONS

The results documented an uneven distribution of health problems in the general population. Psychotropic medicine use was congruent with the distribution of related health problems, which means that the least-educated groups in most need of treatment also had the most-frequent medicine use. Expenses incurred by the individual user did not seem to be a barrier to access to medicines, not even for specific groups of medicine ineligible for reimbursement in Denmark.

摘要

目的

分析普通人群中不同教育程度群体使用不同类别精神药物的情况是否与相关疾病的发生情况相符。

方法

对2000年丹麦健康与发病率调查的数据进行分析。该调查通过对16岁及以上丹麦人口的代表性样本进行面对面访谈开展(n = 16,690)。通过间接标准化分析教育程度群体中四种不同类型精神药物使用情况及相关疾病的患病率。基于整个研究人群计算年龄和性别标准化患病率比(SPR)及95%置信区间。

结果

总体而言,受教育程度最低的两个群体使用精神药物更为频繁,且报告相关疾病的比例高于间接标准化预期。受教育程度最高的两个群体情况则相反(SPR < 100)。尽管部分SPR不显著,但四类精神药物使用者的总体模式相似。

结论

结果表明普通人群中健康问题分布不均。精神药物的使用与相关健康问题的分布相符,这意味着最需要治疗的受教育程度最低群体使用药物也最为频繁。个人使用者的费用似乎并非获取药物的障碍,即使是在丹麦无法报销的特定药物类别也是如此。

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