Björnelius E, Lidbrink P, Jensen J S
Department of Dermatovenereology, Huddinge University Hospital, Karolinska Institutet, Sweden.
Int J STD AIDS. 2000 May;11(5):292-6. doi: 10.1177/095646240001100504.
Urethral swab specimens obtained from 101 men attending an STD clinic were examined for the presence of Mycoplasma genitalium by polymerase chain reaction (PCR) amplification. Fifty patients had non-gonococcal urethritis (NGU), and 51 patients were included as controls without urethritis. M. genitalium DNA was detected in 13 (26%) of the urethritis patients and in 5 (10%) of the control patients (P=0.06). No patient positive for M. genitalium had a simultaneous chlamydial infection. Thus, in the 36 patients with non-chlamydial NGU, the prevalence of M. genitalium infection was 36% (P=0.007 compared with controls). All patients with M. genitalium positive urethritis had a high grade urethritis defined as >10 polymorphonuclear cells per high power microscopical field. Compared with the control group, those with M. genitalium positive urethritis had more often had a history of urethritis than had those with chlamydial NGU or those with M. genitalium negative, non-chlamydial NGU.
对101名到性传播疾病诊所就诊的男性患者采集尿道拭子标本，通过聚合酶链反应（PCR）扩增检测生殖支原体的存在情况。50例患者患有非淋菌性尿道炎（NGU），51例患者作为无尿道炎的对照。在13例（26%）尿道炎患者和5例（10%）对照患者中检测到生殖支原体DNA（P=0.06）。生殖支原体阳性的患者均无衣原体同时感染。因此，在36例非衣原体性NGU患者中，生殖支原体感染率为36%（与对照组相比，P=0.007）。所有生殖支原体阳性尿道炎患者均有严重尿道炎，定义为每高倍显微镜视野多形核细胞>10个。与对照组相比，生殖支原体阳性尿道炎患者比衣原体性NGU患者或生殖支原体阴性的非衣原体性NGU患者更常有尿道炎病史。
