Møller L A, Lose G, Jørgensen T
Department of Obstetrics and Gynaecology, Glostrup County Hospital, University of Copenhagen, DK-2600 Glostrup, Denmark.
BMJ. 2000 May 27;320(7247):1429-32. doi: 10.1136/bmj.320.7247.1429.
To determine the incidence and rates of remission of lower urinary tract symptoms at one year in women aged 40-60, and to assess factors associated with remission.
Ongoing longitudinal cohort study.
One rural and one urban county in Denmark.
4000 women recruited on a random basis, 2860 of whom were followed up at one year.
Incidence and rates of remission of lower urinary tract symptoms.
Prevalence, incidence, and rates of remission of lower urinary tract symptoms in 2284 women were respectively 28.5% (95% confidence interval 26.7% to 30.4%), 10.0% (8.5% to 11.4%), and 27.8% (25.6% to 30.0%). Overall, symptoms were not significantly associated with events performed or initiated in the study period: medical consultation (1.6, 0.8 to 2.8), pelvic floor physiotherapy (0.9, 0.5 to 1.8), treatment with antibiotics on suspicion of a lower urinary tract infection (1.3, 0.8 to 2.2), or other treatment (1.7, 0.7 to 4. 1). Many of the individual symptoms were, however, associated with seeking professional help.
Lower urinary tract symptoms constitute dynamic conditions, with women experiencing more or fewer symptoms, and eventually a cessation of symptoms. The distinction between permanent and fluctuating cases may have important clinical and scientific implications.
确定40至60岁女性一年后下尿路症状的发生率和缓解率，并评估与缓解相关的因素。
正在进行的纵向队列研究。
丹麦的一个农村县和一个城市县。
随机招募4000名女性，其中2860名在一年后接受随访。
下尿路症状的发生率和缓解率。
2284名女性下尿路症状的患病率、发生率和缓解率分别为28.5%（95%置信区间26.7%至30.4%）、10.0%（8.5%至11.4%）和27.8%（25.6%至30.0%）。总体而言，症状与研究期间进行或开始的事件无显著关联：就医咨询（1.6，0.8至2.8）、盆底物理治疗（0.9，0.5至1.8）、怀疑下尿路感染时使用抗生素治疗（1.3，0.8至2.2）或其他治疗（1.7，0.7至4.1）。然而，许多个体症状与寻求专业帮助有关。
下尿路症状是动态变化的情况，女性会经历或多或少的症状，最终症状会停止。区分永久性和波动性病例可能具有重要的临床和科学意义。
