Lien E L, Goodman D B, Rasmussen H
Biochim Biophys Acta. 1976 Feb 24;421(2):210-7. doi: 10.1016/0304-4165(76)90287-7.
The effects of an inhibitor of RNA synthesis, cordycepin, and an inhibitor of protein synthesis, cycloheximide, on aldosterone-induced changes in lipid metabolism and phospholipid fatty acid composition have been studied in the toad urinary bladder. At the concentrations employed, the inhibitors abolish the hormone-induced increases in total lipid synthesis, phospholipid fatty acid specific activities, and weight percentage of phospholipid long-chain polyunsaturated fatty acids as well as blocking the aldosterone-mediated increase in sodium transport.
在蟾蜍膀胱中，研究了RNA合成抑制剂虫草素和蛋白质合成抑制剂放线菌酮对醛固酮诱导的脂质代谢变化及磷脂脂肪酸组成的影响。在所使用的浓度下，这些抑制剂消除了激素诱导的总脂质合成增加、磷脂脂肪酸比活性增加以及磷脂长链多不饱和脂肪酸重量百分比增加，同时也阻断了醛固酮介导的钠转运增加。
