Lee D, Lazova R, Bolognia J L
Department of Dermatology, Yale University School of Medicine, New Haven, Conn. 06520, USA.
Dermatology. 2000;200(3):270-4. doi: 10.1159/000018374.
The classic description of inflammatory vitiligo is an erythematous rim at the periphery of a patch of hypopigmented or depigmented skin. The histological correlate is a superficial perivascular infiltrate of mononuclear cells. However, we observed a 61-year-old patient with inflammatory vitiligo who had thin solid pink scaly plaques as well as serpiginous lesions with fine scale. Histologically, a lichenoid infiltrate was seen as was a thickened stratum corneum with parakeratosis. In a review of the literature, scattered case reports of similar findings were identified, either in the Japanese and French literature or from over 25 years ago. The clinical and histological spectrum of inflammatory vitiligo should be expanded to include solid and annular papulosquamous plaques as well as lichenoid infiltrates with exocytosis.
炎症性白癜风的经典描述是色素减退或色素脱失斑周边的红斑边缘。其组织学对应表现为浅层血管周围单核细胞浸润。然而，我们观察到一名61岁的炎症性白癜风患者，其有薄的实性粉红色鳞屑斑块以及伴有细鳞屑的匐行性损害。组织学上，可见苔藓样浸润以及伴有角化不全的角质层增厚。在文献回顾中，无论是在日本和法国的文献中，还是在25年多以前的文献中，都发现了类似发现的散在病例报告。炎症性白癜风的临床和组织学谱应扩大，以包括实性和环状丘疹鳞屑性斑块以及伴有细胞外渗的苔藓样浸润。
