Benchimol A, dos Santos A, Desser K B
Am J Med. 1976 Mar;60(3):339-43. doi: 10.1016/0002-9343(76)90749-x.
Thirty-two patients from a larger series of subjects undergoing routine postoperative evaluation of the aortocoronary saphenous bypass graft procedure were found to have one (20 patients) or all (12 patients) of the implanted grafts totally occluded. Such occlusion occurred in association with persistent postoperative subjective improvement manifested by a significant diminution or complete disappearance of angina pectoris. Postoperative myocardial infarction was documented in only seven cases, and the possibility of successful partial revascularization could be logically applied to only 20 of these 32 patients. Other suggested mechanisms for relief of angina pectoris in this setting are mentioned, although none is scientifically proved. It is concluded that (1) the marked subjective improvement documented in this population does not universally correlate with anatomic success and that (2) a diminution in the degree of angina pectoris cannot be clinically applied as a reliable indicator of postoperative graft patency.
在接受主动脉冠状动脉大隐静脉搭桥手术常规术后评估的一大组受试者中,发现32例患者的植入移植物有一根(20例患者)或全部(12例患者)完全闭塞。这种闭塞发生时,术后主观症状持续改善,表现为心绞痛明显减轻或完全消失。仅7例记录有术后心肌梗死,在这32例患者中,只有20例在逻辑上有可能成功实现部分血运重建。文中提到了在此情况下缓解心绞痛的其他可能机制,尽管均未得到科学证实。得出的结论是:(1)该人群中记录到的明显主观改善并非普遍与解剖学成功相关;(2)心绞痛程度的减轻不能在临床上作为术后移植物通畅的可靠指标。