ERG of humans without C-wave.

Three out of 18 healthy persons investigated with the DC-ERG do not show a c-wave. By varying the adaptation levels and intensities of the stimuli four components in the human ERG can be isolated, the cone and rod late receptor potentials, the positive DC response, and a c-wave in most subjects. It is suggested that investigation of these components reveals a more detailed understanding of the pathophysiologic mechanisms in some retinal diseases.