Pan J, Takeshita T, Morimoto K
Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Yamada-Oka 2-2, Suita, 565-0871, Osaka, Japan.
Int J Psychophysiol. 2000 Aug;37(2):149-53. doi: 10.1016/s0167-8760(00)00086-6.
The habituation of auditory P300 event-related brain potential (ERP) from single-stimulus paradigm was evaluated and compared to that from oddball paradigm. Three task conditions were: oddball with a button press (oddball/press) response, single-stimulus with a button-press (single-stimulus/press) response and a silent count (single-stimulus/count) response. The oddball/press condition demonstrated larger P300 amplitude and longer latency overall than either single-stimulus condition, but P300 amplitude decreased and peak latency increased similarly over successive trial blocks for all three tasks. Thus, the oddball and single-stimulus ERP tasks produce analogous changes under repeated measurements and indicate that the single-stimulus task can serve as an alternative method for eliciting the P300 in applied and clinical settings.
评估了单刺激范式下听觉P300事件相关脑电位（ERP）的习惯化情况，并与Oddball范式下的情况进行了比较。三种任务条件分别为：按键Oddball（Oddball/按）反应、按键单刺激（单刺激/按）反应和静息计数（单刺激/计数）反应。总体而言，Oddball/按条件下的P300波幅更大，潜伏期更长，比任何一种单刺激条件都要明显，但在所有三项任务的连续试验块中，P300波幅均类似地降低，峰值潜伏期均增加。因此，Oddball和单刺激ERP任务在重复测量下会产生类似的变化，这表明单刺激任务可作为在应用和临床环境中诱发P300的替代方法。
