Polich J, Heine M R
Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA.
Psychophysiology. 1996 Nov;33(6):747-52. doi: 10.1111/j.1469-8986.1996.tb02371.x.
The P300 event-related brain potential (ERP) was elicited with auditory and visual stimuli in two different tasks. The oddball paradigm presented both target and standard stimuli; the single-stimulus paradigm presented a target but no standard stimulus, with the intertarget interval the same as that for the oddball condition. Target probability was .20 for the oddball task, with target stimuli occurring at the same temporal frequency in the single-stimulus paradigm. Scalp topography was assessed with 15 electrode locations. P300 amplitude was larger and latency was longer for the oddball than for single-stimulus procedure. P300 from auditory stimuli was smaller and shorter in latency than that from the visual stimuli, and both modalities showed similar but not identical scalp topographies. The findings suggest that the single-stimulus paradigm may be useful in experimental and applied contexts that require very simple ERP task conditions.
在两项不同任务中，通过听觉和视觉刺激诱发P300事件相关脑电位（ERP）。oddball范式同时呈现目标刺激和标准刺激；单刺激范式只呈现目标刺激而无标准刺激，目标刺激之间的间隔与oddball范式相同。oddball任务的目标概率为0.20，在单刺激范式中目标刺激以相同的时间频率出现。通过15个电极位置评估头皮地形图。与单刺激程序相比，oddball范式的P300波幅更大，潜伏期更长。听觉刺激诱发的P300波幅更小，潜伏期更短，两种模态的头皮地形图相似但不完全相同。研究结果表明，单刺激范式在需要非常简单的ERP任务条件的实验和应用场景中可能有用。
