Plagne R, Chollet P, Guerin D, Chassagne J, Bidet J M, Sauvezie B
Biomedicine. 1975 Dec 20;23(10):447-51.
Determination of electrophoretic mobility of lymphocytes in 70 cancer patients shows a significant decrease of the fast moving cells. It seems to be a relation between the percentage or absolute number of the rapid lymphocytes and dissemination and prognosis of the disease. This decrease is in agreement with the variations of the T lymphocyte population described in cancer patients with other methods. On the contrary, although there is reduction of total blood lymphocytes, the number of slow moving cells is not reduced. The changes observed in mean migration speed of fast and slow migrating lymphocytes could indicate more selective alterations in some cell subpopulations.
对70例癌症患者淋巴细胞电泳迁移率的测定显示，快速移动细胞显著减少。快速淋巴细胞的百分比或绝对数量似乎与疾病的播散和预后之间存在关联。这种减少与用其他方法描述的癌症患者T淋巴细胞群体的变化一致。相反，尽管全血淋巴细胞数量减少，但慢速移动细胞的数量并未减少。快速和慢速迁移淋巴细胞平均迁移速度的变化可能表明某些细胞亚群发生了更具选择性的改变。
