Bauer H W, Ax W
Br J Cancer. 1977 Dec;36(6):708-12. doi: 10.1038/bjc.1977.253.
A simple rapid micro-agglutination test for detecting sensitized lymphocytes from human peripheral blood is described: the poly-L-lysine (PLL) 3400 agglutination test of lymphocytes (PAL test). The incubation of lymphocytes from 30 cancer patients, 30 patients with non-malignant disease and 40 healthy controls with PLL (mol. wt 3400) is evaluated. The test was positive in 83 percent of malignant and 20 percent of non-malignant cases. All healthy controls were negative. Other peptides tested showed no significant difference in reaction between malignant and non-malignant diseases. The mechanism of detection of sensitized lymphocytes from patients with malignant disease through agglutination induced by PLL 3400 is discussed.
淋巴细胞的聚-L-赖氨酸（PLL）3400凝集试验（PAL试验）。对30例癌症患者、30例非恶性疾病患者和40例健康对照的淋巴细胞与PLL（分子量3400）的孵育情况进行了评估。该试验在83%的恶性病例和20%的非恶性病例中呈阳性。所有健康对照均为阴性。测试的其他肽在恶性和非恶性疾病之间的反应无显著差异。本文还讨论了通过PLL 3400诱导凝集来检测恶性疾病患者致敏淋巴细胞的机制。
