Barrett S F, Wilcox M
Department of Electrical Engineering, University of Wyoming, Laramie, USA.
Biomed Sci Instrum. 2000;36:263-8.
We have developed an algorithm to track a rat swimming in a Morris Water Maze. It provides an update on rodent position 15 times per second. The tracking algorithm uses a rotation insensitive tracking template coupled with a limited exhaustive search technique to maintain lock on the moving rat. At the completion of the run, the relative time the rat spent in each quadrant is reported. The tracking algorithm was successfully used to evaluate the time course of memory loss and correlate that to tissue loss in the rat cortex following blunt trauma to the sensory cortex. Results of that study are reported in another paper. Our project budget did not allow for commercially available software to perform the tracking task which typically provide position updates 10 times per second. This paper focuses on the tracking algorithm and support equipment used to measure the rats' progress in the maze.
我们开发了一种算法来跟踪在莫里斯水迷宫中游泳的大鼠。它每秒提供15次啮齿动物位置的更新。该跟踪算法使用一个对旋转不敏感的跟踪模板，结合有限的穷举搜索技术来锁定移动的大鼠。在实验结束时，报告大鼠在每个象限所花费的相对时间。该跟踪算法已成功用于评估钝性创伤感觉皮层后大鼠记忆丧失的时间进程，并将其与大鼠皮层中的组织损失相关联。该研究结果在另一篇论文中报告。我们的项目预算不允许使用通常每秒提供10次位置更新的商业软件来执行跟踪任务。本文重点介绍了用于测量大鼠在迷宫中行进情况的跟踪算法和支持设备。
