Woo P C, Lum P N, Wong S S, Cheng V C, Yuen K Y
Department of Microbiology, The University of Hong Kong, Queen Mary Hospital.
Eur J Clin Microbiol Infect Dis. 2000 Apr;19(4):294-7. doi: 10.1007/s100960050478.
In ten hospitalised patients with cellulitis complicating lymphoedema encountered over a 3-year period (1996-1998), the underlying diseases were carcinoma of the cervix (n = 4), uterus (n = 1), vagina (n = 1), breast (n=2) and nasopharynx (n= 1), and retroperitoneal squamous cell carcinoma (n = 1). Three of the ten patients had positive blood cultures, compared to none of the 20 age-matched, sex-matched controls hospitalised for cellulitis without lymphoedema. The mean duration of fever, tachycardia and cellulitis was significantly longer in patients with lymphoedema than in those without (P<0.05, P<0.05, and P<0.005 respectively). Early treatment initiated by patients themselves may help stop bacterial replication in the initial stages and minimise further damage to the lymphatic system.
在1996年至1998年的3年期间，我们遇到了10例蜂窝织炎并发淋巴水肿的住院患者，其基础疾病包括宫颈癌（n = 4）、子宫癌（n = 1）、阴道癌（n = 1）、乳腺癌（n = 2）、鼻咽癌（n = 1）以及腹膜后鳞状细胞癌（n = 1）。这10例患者中有3例血培养呈阳性，而20例年龄和性别匹配的、因无淋巴水肿的蜂窝织炎住院的对照患者血培养均为阴性。淋巴水肿患者的发热、心动过速及蜂窝织炎的平均持续时间显著长于无淋巴水肿的患者（分别为P<0.05、P<0.05和P<0.005）。患者自身尽早开始治疗可能有助于在初始阶段阻止细菌繁殖，并将对淋巴系统的进一步损害降至最低。
