Gao K, Orgel L E
The Salk Institute for Biological Studies, San Diego, CA 92186-5800, USA.
Orig Life Evol Biosph. 2000 Feb;30(1):45-51. doi: 10.1023/a:1006683507864.
Oligonucleotide 5'-polyphosphates are formed under potentially prebiotic conditions from oligonucleotide 5'-phosphates and sodium trimetaphosphate. Oligonucleotides activated as polyphosphates undergo template-directed ligation. We believe that these reactions could have produced longer oligonucleotide products from shorter substrates under prebiotic conditions.
在潜在的益生元条件下，寡核苷酸5'-多磷酸盐由寡核苷酸5'-磷酸盐和三偏磷酸钠形成。被激活为多磷酸盐的寡核苷酸会进行模板导向的连接反应。我们认为，在益生元条件下，这些反应能够从较短的底物产生更长的寡核苷酸产物。
