Greger H, Pacher T, Vajrodaya S, Bacher M, Hofer O
Comparative Phytochemistry Department, Institute of Botany, University of Vienna, Rennweg 14, A-1030 Wien, Austria.
J Nat Prod. 2000 May;63(5):616-20. doi: 10.1021/np990542y.
Six new amides, leptaglin (1), hemileptaglin (2), aglanthin (3), agleptin (4), isoagleptin (5), and leptanthin (6), together with known lignans yangambin, eudesmin, grandisin (7), epigrandisin (8), and dehydrodiconiferyl alcohol, were isolated and identified from the lipophilic leaf and stem bark extracts of Aglaia leptantha. The dominating sulfur-containing bisamides contained either putrescine or the corresponding pyrrolidine ring as the diamine part, linked to phenylacetic and/or methylthiopropenoic acid moieties showing a remarkable infraspecific variation in eight individuals from two different habitats. Structures were determined by MS and NMR, including lanthanide-induced shifts.
从菲律宾米仔兰（Aglaia leptantha）的亲脂性叶和茎皮提取物中分离并鉴定出六种新酰胺，即菲律宾米仔兰酰胺（1）、半菲律宾米仔兰酰胺（2）、米仔兰凝集素（3）、米仔兰凝集素（4）、异米仔兰凝集素（5）和菲律宾米仔兰黄素（6），以及已知的木脂素洋橄榄苦苷、桉叶素、大戟素（7）、表大戟素（8）和脱氢二松柏醇。主要的含硫双酰胺含有腐胺或相应的吡咯烷环作为二胺部分，与苯乙酸和/或甲基硫代丙酸部分相连，在来自两个不同栖息地的八个个体中表现出显著的种下变异。通过质谱和核磁共振（包括镧系元素诱导位移）确定了结构。
