Lindahl P, Gresser I, Leary P, Tovey M
J Infect Dis. 1976 Jun;133 Suppl:A66-8. doi: 10.1093/infdis/133.supplement_2.a66.
Treatment of young and mature mice with potent preparations of mouse interferon results in a marked enhancement of the expression of histocompatibility antigens on the surface of thymocytes and splenic lymphocytes, as measured by an enhanced absorption of alloantiserum. These modifications in the expression of cell surface antigens may reflect an effect of interferon on lymphocyte naturation and may be relevant to theffect of interferon on lymphocyte function.
用强效的小鼠干扰素制剂处理幼年和成年小鼠,结果显示,通过同种异体抗血清吸收增强来测定,胸腺细胞和脾淋巴细胞表面的组织相容性抗原表达显著增强。细胞表面抗原表达的这些改变可能反映了干扰素对淋巴细胞成熟的影响,并且可能与干扰素对淋巴细胞功能的影响有关。