Takahashi Y, Fujimaki S, Kobayashi T, Morita T, Higuchi T
MS Application Laboratory, Application and Research Center, Analytical Instrument Division, JEOL Ltd., 3-1-2 Musashino, Akishima, Tokyo 196-0021, Japan.
Rapid Commun Mass Spectrom. 2000;14(11):947-9. doi: 10.1002/(SICI)1097-0231(20000615)14:11<947::AID-RCM970>3.0.CO;2-N.
A new technique for accurate mass determination by using multiple sprayers nano-electrospray ionization mass spectrometry (nano-ESI-MS) on a magnetic sector instrument is described. Metal coated glass capillaries were used as nano-ESI sprayers. One of the sprayers was used for the reference compound solution, and others were used for the introduction of sample solutions. The spectra of the different compounds were obtained by shifting each sprayer's position relative to the sampling orifice. The accurate masses of several standard compounds were obtained with good accuracy, without problems arising from differences in ionization efficiency between the sample compounds and reference compound.
描述了一种通过在磁扇形仪器上使用多个喷雾器的纳米电喷雾电离质谱（nano-ESI-MS）进行精确质量测定的新技术。金属涂层玻璃毛细管用作纳米电喷雾器。其中一个喷雾器用于参考化合物溶液，其他喷雾器用于引入样品溶液。通过相对于采样孔移动每个喷雾器的位置来获得不同化合物的光谱。获得了几种标准化合物的精确质量，准确度良好，不存在样品化合物和参考化合物之间电离效率差异引起的问题。
