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[流行性腮腺炎脑膜炎患者血液及脑脊液中的B淋巴细胞和T淋巴细胞(作者译)]

[Blood and cerebrospinal fluid B and T lymphocytes in mumps-meningitis (author's transl)].

作者信息

Traugott U, Eibl M, Weippl G, Harasek G

出版信息

Padiatr Padol. 1976;11(3):545-53.

PMID:1084508
Abstract

20 children, 12 boys and 8 girls, with mumps-meningitis have been investigated during the acute stage of illness. Immunoglobulin-concentration, B and T cell ratios were determined in venous blood and cerebrospinal fluid. In the blood no correlation between the percentage of B cells and immunoglobulin-levels, or the course of illness could be observed. Total protein level as well as cell count, the concentration of glucose and chloride were determined in the cerebrospinal fluid at the same time. No correlation between the percentage of B cells and immunoglobulin-levels could be observed in cerebrospinal fluid. No difference in the number of B and T cells was observed between blood and cerebrospinal fluid. These results demonstrate, that the lymphocytes in cerebrospinal fluid in meningitis possess the same surface markers and show about the same B to T cell ratio as it is found on the lymphocytes of blood.

摘要

对20名患有腮腺炎脑膜炎的儿童进行了研究,其中12名男孩,8名女孩,研究在疾病急性期进行。测定了静脉血和脑脊液中的免疫球蛋白浓度、B细胞和T细胞比例。在血液中,未观察到B细胞百分比与免疫球蛋白水平或病程之间存在相关性。同时测定了脑脊液中的总蛋白水平以及细胞计数、葡萄糖和氯化物浓度。在脑脊液中未观察到B细胞百分比与免疫球蛋白水平之间存在相关性。血液和脑脊液中的B细胞和T细胞数量没有差异。这些结果表明,脑膜炎患者脑脊液中的淋巴细胞具有相同的表面标志物,其B细胞与T细胞的比例与血液中的淋巴细胞大致相同。

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