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[420例发生心肌梗死的半农村人口冠状动脉风险的流行病学研究]

[Epidemiology of the coronary risk in a semi-rural population of 420 patients having presented a myocardial infarct].

作者信息

Briquemont F, Vrydagh S, Kornitzer M, Smets P

出版信息

Acta Cardiol. 1975;30(6):427-54.

PMID:1084664
Abstract

Various sociological and biological parameters have been studied in a population of 420 subjects - 335 men and 85 women - living in a semi rural country and having presented a myocardial infarct. Our study shows big differences in epidemiology between men and women: 1. The age of women is on an average seven years older than men (63 years against 56). 2. The women's average rate of cholesterol oversteps men's rate by 21 mg% (291 mg % against 271). 3. The blood pressure, systolic and diastolic, is distinctly higher by women (mean 171/97) tan by men (148/98). Amid women, 63% have a S.B.P. equal to or higher than 160 mm Hg against 23% by men and 56% have a D.B.P. equal to or higher than 100 mm Hg against 21 % by men. 4. Hyperglycemia is more frequent among women; man rate: 103 mg % against 88 mg % by men; 17 % of the women have an equal to or higher rate than 110 mg % (8 % among men). 5. Obesity, expressed by a weight index, equal to or higher than 120, is found in 76 % of the women and 34 % of the men. The mean index is 123 by the women and 115 by the men. 6. Cigarette smoking is far more important by men: 65 % of the men smoke at least 15 cigarettes a day with smoke inhalation. This factor is practically not met by women. The smokers get their myocardial infarct at a significantly lower age than no smoking men and women. The women of our infarct population have thus an age, a cholesterol rate, a blood pressure and a glycemia higher than men of the same population; they are more frequently overweight but they don't smoke. Consequently, metabolic agents seem to play an essential part in coronary risk in women.

摘要

我们对居住在半乡村地区且曾患心肌梗死的420名受试者(335名男性和85名女性)的各种社会学和生物学参数进行了研究。我们的研究表明,男性和女性在流行病学方面存在很大差异:1. 女性的平均年龄比男性大7岁(63岁对56岁)。2. 女性的平均胆固醇水平比男性高21毫克%(291毫克%对271毫克%)。3. 女性的收缩压和舒张压明显高于男性(平均171/97)(男性为148/98)。在女性中,63%的人收缩压等于或高于160毫米汞柱,男性为23%;56%的人舒张压等于或高于100毫米汞柱,男性为21%。4. 高血糖在女性中更为常见;女性血糖水平为103毫克%,男性为88毫克%;17%的女性血糖水平等于或高于110毫克%(男性为8%)。5. 以体重指数等于或高于120表示的肥胖,在76%的女性和34%的男性中存在。女性的平均指数为123,男性为115。6. 男性吸烟情况更为严重:65%的男性每天至少吸入15支香烟。女性几乎不存在这种情况。吸烟者发生心肌梗死的年龄明显低于不吸烟的男性和女性。因此,我们梗死人群中的女性比同人群中的男性年龄更大、胆固醇水平更高、血压更高、血糖更高;她们更常超重但不吸烟。所以,代谢因素似乎在女性冠心病风险中起重要作用。

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