Khan A, Thometz D, Garrison O, Hill J M
Ann Allergy. 1976 May;36(5):330-6.
The effect of transfer factor (TF) on E-rosettes (ER) was studied in vivo in a patient with Hodgkin's disease. Transfer factor was given in doses of 10 units/sq m intramuscularly. The ER forming cells and the ER scores were determined. The ER score method took into account the number of erythrocytes in each rosette. The increase in ER score was maximum at 24 hours and it declined during the following one to two weeks. It was suggested that TF may have to be given more frequently than indicated by the persistence of skin reactivity. TF was fractionated with high pressure liquid chromatography. Fraction 2 increased ER in a patient with Schwannoma. Non-specificity of TF was also discussed.
在一名霍奇金病患者体内研究了转移因子（TF）对E玫瑰花结（ER）的影响。转移因子以10单位/平方米的剂量肌肉注射。测定了ER形成细胞和ER评分。ER评分方法考虑了每个玫瑰花结中的红细胞数量。ER评分在24小时时增加最多，在接下来的一到两周内下降。有人提出，转移因子的给药频率可能需要比皮肤反应持续时间所表明的更频繁。用高压液相色谱法对转移因子进行了分级分离。在一名神经鞘瘤患者中，第2级分增加了ER。还讨论了转移因子的非特异性。
