[Treatment of Hodgkin's malignant lymphoma in children and adolescents by immunomodulation with a dialysate of human leukocytes].

The authors assessed in a group of children with malignant lymphoma the effect of dialysate of human leucocytes on some immunological indicators. Assessment of T lymphocytes by the E rosette test before and after administration of a dialysate of human leucocytes did not reveal any significant changes in the number of T lymphocytes. Similarly the assessed number of NK cells in the peripheral blood stream was not markedly affected. The immunostimulating action was manifested by an increased activation of lymphocytes assessed by the nuclear test and the blastic transformation test. In lymphocytic sub-populations examined by means of monoclonal antibodies a rise of CD4+ and T lymphocytes was recorded.