Daltrey I R, Kissin M W
Department of Surgery, The Royal Surrey County Hospital, Guildford, UK.
Br J Surg. 2000 Jun;87(6):777-9. doi: 10.1046/j.1365-2168.2000.087006777.x.
Breast fine-needle aspiration cytology (FNAC) is an invasive investigation which can be uncomfortable or distressing. This randomized study investigated the discomfort of breast FNAC and the effect of different techniques.
Some 116 FNAC samples were taken from 98 women with a palpable breast mass. Each patient was randomized to one of four study groups; aspiration was performed using a green-hub (21 G) or blue-hub (23 G) needle, either with or without local anaesthetic. Each patient scored the pain of the whole procedure using a visual analogue scale.
A green-hub needle caused significantly more discomfort (mean(s.e.m.) pain score 5.1(0. 4) cm) than a blue-hub needle (2.9(0.4) cm), or either a blue- or green-hub needle with local anaesthetic (3.0(0.4) and 2.1(0.4) cm respectively) (F = 10.28, 3112 d.f., P < 0.01, analysis of variance).
The discomfort of breast FNAC is dependent upon the gauge of the needle and the use of local anaesthetic. A blue-hub needle without local anaesthetic should be first choice for breast FNAC.
乳房细针穿刺细胞学检查（FNAC）是一种侵入性检查，可能会让人感到不适或痛苦。这项随机研究调查了乳房FNAC的不适感以及不同技术的效果。
从98名可触及乳房肿块的女性中采集了约116份FNAC样本。每位患者被随机分配到四个研究组之一；使用绿色针座（21G）或蓝色针座（23G）的针头进行穿刺，有无局部麻醉。每位患者使用视觉模拟量表对整个操作过程的疼痛程度进行评分。
绿色针座的针头引起的不适感明显更强（平均（标准误）疼痛评分5.1（0.4）cm），高于蓝色针座的针头（2.9（0.4）cm），也高于使用局部麻醉的蓝色或绿色针座针头（分别为3.0（0.4）和2.1（0.4）cm）（F = 10.28，自由度为3、112，P < 0.01，方差分析）。
乳房FNAC的不适感取决于针头的规格和局部麻醉的使用。对于乳房FNAC，不使用局部麻醉的蓝色针座针头应作为首选。
