针头尺寸对头颈部细针穿刺细胞学检查中疼痛、样本充足性及准确性影响的前瞻性随机临床试验。
Prospective randomized clinical trial of the effect of needle size on pain, sample adequacy and accuracy in head and neck fine-needle aspiration cytology.
作者信息
Brennan Peter A, Mackenzie Neil, Oeppen Rachel S, Kulamarva Gautham, Thomas Gareth J, Spedding Anne V
机构信息
Maxillofacial Surgery Department, Queen Alexandra Hospital, Southwick Hill Road, Cosham, Portsmouth, United Kingdom.
出版信息
Head Neck. 2007 Oct;29(10):919-22. doi: 10.1002/hed.20601.
BACKGROUND
Fine-needle aspiration cytology (FNAC) is useful in the diagnosis of many conditions of the head and neck. No reported studies have investigated the optimal needle gauge in the head and neck region.
METHODS
This was a prospective randomized trial of 100 patients who required FNAC performed with either a 21G or 23G needle. Discomfort was scored by patients using a visual analogue scale. Sample accuracy was assessed in patients who subsequently had excision biopsy.
RESULTS
FNAC performed with a 23G needle was less painful (mean +/- SE, 1.6 +/- 1.01) than FNAC with a 21G needle (3.3 +/- 1.94; p < .001). There was no difference in sample adequacy between the 2 needle sizes (p = .59). The sensitivities and specificities of both needles were similar.
CONCLUSION
Head and neck FNAC should routinely be performed with a 23G needle, resulting in less patient discomfort, and giving sample adequacy comparable to a conventional 21G needle.
背景
细针穿刺细胞学检查（FNAC）在许多头颈部疾病的诊断中很有用。尚无报道研究头颈部区域的最佳针径。
方法
这是一项对100例需要进行FNAC检查的患者进行的前瞻性随机试验，分别使用21G或23G针进行操作。患者使用视觉模拟量表对不适程度进行评分。对随后进行切除活检的患者评估样本准确性。
结果
使用23G针进行FNAC的疼痛程度（均值±标准误，1.6±1.01）低于使用21G针（3.3±1.94；p<0.001）。两种针径的样本充足率无差异（p=0.59）。两种针的敏感性和特异性相似。
结论
头颈部FNAC应常规使用23G针进行，可减少患者不适，并提供与传统21G针相当的样本充足率。
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