Ignelzi R J, Nyquist J K
J Neurosurg. 1976 Aug;45(2):159-65. doi: 10.3171/jns.1976.45.2.0159.
Experiments were performed with a peripheral neurostimulator, used clinically for pain relief, on isolated cat cutaneous peripheral nerve to determine the effect of electrical stimulation on components of the compound action potential. The results show that neurostimulation alters the conduction velocity and the amplitude of both the A-alpha and beta and the A-delta waves with the more slowly-conducting A-delta component showing the greatest changes. This direct alteration of peripheral nerve activity distal to the first synapse in the spinal cord might contribute to the mechanism of pain relief.
使用临床上用于缓解疼痛的外周神经刺激器对分离的猫皮肤外周神经进行实验，以确定电刺激对复合动作电位成分的影响。结果表明，神经刺激会改变A-α和β以及A-δ波的传导速度和幅度，传导较慢的A-δ成分变化最大。脊髓中第一个突触远端的外周神经活动的这种直接改变可能有助于疼痛缓解机制。
