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一名核型为46, XX的女性患卵巢性腺母细胞瘤合并混合性生殖细胞肿瘤且妊娠成功。

Ovarian gonadoblastoma with mixed germ cell tumor in a woman with 46, XX karyotype and successful pregnancies.

作者信息

Zhao S, Kato N, Endoh Y, Jin Z, Ajioka Y, Motoyama T

机构信息

Department of Pathology, Yamagata University School of Medicine, Yamagata, Japan.

出版信息

Pathol Int. 2000 Apr;50(4):332-5. doi: 10.1046/j.1440-1827.2000.01041.x.

Abstract

An extremely rare case of unilateral gonadoblastoma with mixed germ cell tumor arising in the ovary of a 27-year-old woman with 46,XX karyotype and two successful pregnancies is reported. The mixed germ cell tumor was composed of choriocarcinoma, embryonal carcinoma, yolk sac tumor, immature teratoma and dysgerminoma. The patient has been well, without evidence of disease for over 10 years since her first surgery and adjuvant chemotherapy.

摘要

报告了一例极其罕见的病例,一名核型为46,XX且有两次成功妊娠史的27岁女性卵巢发生单侧性腺母细胞瘤并伴有混合性生殖细胞肿瘤。混合性生殖细胞肿瘤由绒毛膜癌、胚胎癌、卵黄囊瘤、未成熟畸胎瘤和无性细胞瘤组成。自首次手术及辅助化疗以来,该患者状况良好,超过10年无疾病证据。

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