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一名核型为46XX的女孩,一侧卵巢为含无性细胞瘤的性腺母细胞瘤,对侧卵巢为含无性细胞瘤和卵黄囊瘤的性腺母细胞瘤。

Gonadoblastoma with dysgerminoma in one ovary and gonadoblastoma with dysgerminoma and yolk sac tumor in the contralateral ovary in a girl with 46XX karyotype.

作者信息

Obata N H, Nakashima N, Kawai M, Kikkawa F, Mamba S, Tomoda Y

机构信息

Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Japan.

出版信息

Gynecol Oncol. 1995 Jul;58(1):124-8. doi: 10.1006/gyno.1995.1195.

Abstract

A case of gonadoblastoma with dysgerminoma in the left ovary and gonadoblastoma with dysgerminoma and yolk sac tumor in the right of a 10-year-old girl is reported. Her karyotype was 46XX, normal female type. A case of a gonadoblastoma without a Y chromosome is very rare. Furthermore, the prognosis for gonadoblastoma accompanied by germ cell tumors other than dysgerminoma was very poor in the past, but the patient remains well 25 months after the first operation.

摘要

报告了一名10岁女孩,左侧卵巢为含无性细胞瘤的性腺母细胞瘤,右侧为含无性细胞瘤和卵黄囊瘤的性腺母细胞瘤。她的核型为46XX,正常女性型。无Y染色体的性腺母细胞瘤病例非常罕见。此外,过去伴有非无性细胞瘤的生殖细胞肿瘤的性腺母细胞瘤预后很差,但该患者在首次手术后25个月仍状况良好。

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