Black D W, Okiishi C, Schlosser S
Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242-1000, USA.
Psychosomatics. 2000 May-Jun;41(3):253-61. doi: 10.1176/appi.psy.41.3.253.
The authors assessed self-reported health status and clinical symptoms in people reporting multiple chemical sensitivities (MCS) at a 9-year follow-up interview using structured and semistructured instruments and self-report questionnaires. Of the original sample, 18 people (69%) consented to an interview. By use of the best estimate diagnostic method, 15 subjects (83%) met DSM-IV criteria for a lifetime mood disorder, 10 (56%) for a lifetime anxiety disorder, and 10 (56%) for a lifetime somatoform disorder. None of the subjects met the criteria for a substance use disorder (current or lifetime). The Illness Behavior Questionnaire and the Symptom Check-list-90-Revised results showed little change from 1988 and remained significantly different from the control group on many subscales. The authors conclude that the subjects remain strongly committed to the diagnosis of MCS, and although improved since their original interview, many remain symptomatic and continue to report ongoing lifestyle changes.
作者在一项为期9年的随访访谈中，使用结构化和半结构化工具以及自我报告问卷，评估了自述有多种化学物质过敏（MCS）的人群的自述健康状况和临床症状。在原始样本中，18人（69%）同意接受访谈。通过使用最佳估计诊断方法，15名受试者（83%）符合DSM-IV中终身心境障碍的标准，10名（56%）符合终身焦虑障碍的标准，10名（56%）符合终身躯体形式障碍的标准。没有受试者符合物质使用障碍（当前或终身）的标准。疾病行为问卷和症状自评量表-90修订版的结果显示，自1988年以来变化不大，在许多子量表上与对照组仍有显著差异。作者得出结论，受试者仍然坚定地坚持MCS的诊断，尽管自最初访谈以来有所改善，但许多人仍有症状，并继续报告持续的生活方式变化。
