Lin V W, Hsiao I N, Dhaka V
Functional Magnetic Stimulation Laboratory, Spinal Cord Injury/Disorder Health Care Group VAMC Long Beach, CA 90822, USA.
IEEE Trans Biomed Eng. 2000 May;47(5):600-10. doi: 10.1109/10.841332.
Our studies have demonstrated effective stimulation of the bladder, bowel, and expiratory muscles in patients with spinal cord injury using functional magnetic stimulation. However, one limitation of the magnetic coils (MC) is related to their inability to specifically stimulate the target tissue without activation of surrounding tissue. The primary goal of this study was to determine the governing parameters in the MC design, such as coil configuration, diameter, and number of turns in one loop of the coil. By varying these parameters, our approach was to design, construct, and evaluate the induced electric field distributions of two sets of novel MC's. Based on the slinky coil design, the first set of coils was constructed to compare their abilities in generating induced electric fields for focal nerve excitation. The second set of coils was built to determine the effect that changes in two parameters, coil diameter and number of turns in one loop, had on field penetration. The results showed that the slinky coil design produced more focalized stimulation when compared to the planar round coils. The primary-to-secondary peak ratios of the induced electric field from slinky 1 to 5 were 1.00, 2.20, 2.85, 2.62, and 3.54. We also determined that coils with larger diameters had better penetration than those with smaller diameters. Coils with less number of turns in one loop had higher initial field strengths; when compared to coils that had more turns per loop, initial field strengths remained higher as distance from the coil increased. In our attempt to customize MC design according to each functional magnetic stimulation application and patients of different sizes, the parameters of MC explored in this study may facilitate designing an optimal MC for a certain clinical application.
我们的研究表明,使用功能性磁刺激可有效刺激脊髓损伤患者的膀胱、肠道和呼气肌。然而,磁线圈(MC)的一个局限性在于它们无法在不激活周围组织的情况下特异性地刺激目标组织。本研究的主要目的是确定MC设计中的控制参数,如线圈配置、直径和线圈单环匝数。通过改变这些参数,我们的方法是设计、构建并评估两组新型MC的感应电场分布。基于螺旋线圈设计,构建了第一组线圈以比较它们产生用于局灶性神经兴奋的感应电场的能力。构建第二组线圈以确定两个参数(线圈直径和单环匝数)的变化对场穿透的影响。结果表明,与平面圆形线圈相比,螺旋线圈设计产生的刺激更具聚焦性。螺旋线圈1至5的感应电场的初级与次级峰值比分别为1.00、2.20、2.85、2.62和3.54。我们还确定,直径较大的线圈比直径较小的线圈具有更好的穿透性。单环匝数较少的线圈具有较高的初始场强;与每环匝数较多的线圈相比,随着与线圈距离的增加,初始场强保持较高。在我们根据每种功能性磁刺激应用和不同体型的患者定制MC设计的尝试中,本研究探索的MC参数可能有助于为特定临床应用设计最佳的MC。