Papazov Sava P, Daskalov Ivan K
Center of Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Biomed Eng Online. 2002 May 14;1:1. doi: 10.1186/1475-925x-1-1.
Electromagnetic stimulation of the nervous system has the advantage of reduced discomfort in activating nerves. For brain structures stimulation, it has become a clinically accepted modality. Coil designs usually consider factors such as optimization of induced power, focussing, field shape etc. In this study we are attempting to find the effect of the coil contour shape on the electrical field distribution for magnetic stimulation.
We use the maximum of the induced electric field stimulation in the region of interest as the optimization criterion. This choice required the application of the calculus of variation, with the contour perimeter taken as a pre-set condition. Four types of coils are studied and compared: circular, square, triangular and an 'optimally' shaped contour. The latter yields higher values of the induced electrical field in depths up to about 30 mm, but for depths around 100 mm, the circular shape has a slight advantage. The validity of the model results was checked by experimental measurements in a tank with saline solution, where differences of about 12% were found. In view the accuracy limitations of the computational and measurement methods used, such differences are considered acceptable.
We applied an optimization approach, using the calculus of variation, which allows to obtain a coil contour shape corresponding to a selected criterion. In this case, the optimal contour showed higher intensities for a longer line along the depth-axis. The method allows modifying the induced field structure and focussing the field to a selected zone or line.
对神经系统进行电磁刺激在激活神经时具有减少不适感的优势。对于脑结构刺激而言,它已成为一种临床认可的方式。线圈设计通常会考虑诸如感应功率优化、聚焦、场形状等因素。在本研究中,我们试图探究线圈轮廓形状对磁刺激电场分布的影响。
我们将感兴趣区域内感应电场刺激的最大值作为优化标准。这种选择需要应用变分法,并将轮廓周长作为预设条件。研究并比较了四种类型的线圈:圆形、方形、三角形和“最优”形状的轮廓。对于深度达约30毫米的情况,后者产生的感应电场值更高,但对于深度约100毫米的情况,圆形形状具有轻微优势。通过在装有盐溶液的水槽中进行实验测量来检验模型结果的有效性,发现两者存在约12%的差异。鉴于所使用的计算和测量方法的精度限制,这种差异被认为是可接受的。
我们应用了一种采用变分法的优化方法,该方法能够获得与选定标准相对应的线圈轮廓形状。在这种情况下,最优轮廓在沿深度轴的较长线段上显示出更高的强度。该方法允许改变感应场结构并将场聚焦到选定区域或线段。