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[The revaccination against diphtheria and tetanus with adsorbed DT-m anatoxin of children having solid tumors in their case histories].

作者信息

Karpocheva S V, Kostinov M P, Zaeva G E, Gurvich E B, Zaĭtseva L A, Gavrilova G L, Korotkova O V, Kuznetsova A V

机构信息

Mechnikov Research Institute for Vaccines and Sera, Research Institute of Child Oncology and Hematology, Moscow, Russia.

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1999 Jul-Aug(4):46-9.

Abstract

Data on the safety and effect of the vaccination of children with solid tumors are presented. As revealed in this study, the injection of adsorbed DT-m toxoid with reduced antigen content at the period of remission does not induce the relapse of the disease and leads to the production of specific antitoxic antibodies on the protective level. The study has shown that complex antitumor treatment does not essentially affect the formation of specific immune response, though prolonged changes in cell-mediated immunity can be observed.

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