Shirama K, Takeo Y, Shimizu K, Maekawa K
Endocrinol Jpn. 1975 Dec;22(6):575-9. doi: 10.1507/endocrj1954.22.575.
Effects of monoamines or its precursors on the induction of persistent estrus by testosterone propionate (T.P.) were studied in Wistar strain female rats. Daily treatment with 5-hydroxytryptophane (5-HTP) for the first 10 days of life delayed the occurrence of persistent estrus in rats given T.P. at 4 days of age. The onset of persistent estrus occurred in this group of animals at 67.1+/-2.5 days of age compared with 45.1+/-1.4 days of age for the saline treated control group. The role of hypothalamic monoamines in contributing to the induction of persistent estrus by T.P. treatment of neonatal rats is discussed.
在Wistar品系雌性大鼠中研究了单胺类物质或其前体对丙酸睾酮（T.P.）诱导持续性发情的影响。在出生后的前10天每天用5-羟色氨酸（5-HTP）处理，可延迟4日龄给予T.P.的大鼠持续性发情的出现。该组动物持续性发情的开始时间为67.1±2.5日龄，而生理盐水处理的对照组为45.1±1.4日龄。讨论了下丘脑单胺类物质在新生大鼠经T.P.处理诱导持续性发情过程中的作用。
