Njenga M J, Kang'ethe E K, Bwangamoi O, Munyua S J, Mugera G M, Mutiga E R
Faculty of Veterinary Medicine, University of Nairobi, Kabete, Kenya.
J S Afr Vet Assoc. 1999 Dec;70(4):161-3. doi: 10.4102/jsava.v70i4.788.
Experimental transmission of Besnoitia caprae from naturally chronically-infected goats to susceptible ones was achieved by intra-nasal instillation and intra-conjunctival inoculation of cystozoite-containing suspensions, subcutaneous implantation of fascia containing cysts and alternate needle pricking between the infected and non-infected goats. Typical chronic symptoms developed in the fascia-infected does. Cystozoite inoculation into the eyes and mouth did not result in infection. Kids born of dams with acute and chronic besnoitiosis did not contract the infection in utero, suggesting that intra-uterine transmission may not occur. In contrast to does with acute besnoitiosis, which occasionally aborted, the does with chronic besnoitiosis gave birth to healthy kids. Kids below the age of 4 months (pre-weaned period) born of both infected and non-infected does were susceptible to besnoitiosis but appeared to be more resistant than adult goats.
通过鼻内滴注含包囊子孢子的悬液、结膜内接种含包囊子孢子的悬液、皮下植入含囊肿的筋膜以及在感染山羊和未感染山羊之间交替针刺，实现了将山羊贝诺孢子虫从自然慢性感染山羊传播给易感山羊。在筋膜感染的母羊中出现了典型的慢性症状。向眼睛和口腔接种包囊子孢子未导致感染。患有急性和慢性贝诺孢子虫病的母羊所生的羔羊在子宫内未感染，这表明可能不会发生子宫内传播。与偶尔流产的急性贝诺孢子虫病母羊不同，慢性贝诺孢子虫病母羊产下了健康的羔羊。感染和未感染母羊所生的4个月龄以下（断奶前期）羔羊易患贝诺孢子虫病，但似乎比成年山羊更具抵抗力。
