Schneider B, Schnells G, Trentz O, Tscherne H
Chirurg. 1976 Apr;47(4):185-8.
A report of the results of a multicenter study including 4686 patients concerning the therapeutic value of Trasylol (Aprotinin) in traumatic shock. The group treated additionally with Trasylol showed, beside a reduced overall mortality, a statistically significant reduction of mortality in those treated within the first 30 min after the injury. Surgery performed in the posttraumatic stage showed a lower mortality in the Trasylol group. The importance of a time factor in shock treatment and the effects of Trasylol in traumatic shock are emphasized.
一项多中心研究的结果报告，该研究纳入了4686例患者，涉及抑肽酶在创伤性休克中的治疗价值。接受抑肽酶额外治疗的组除了总体死亡率降低外，在受伤后30分钟内接受治疗的患者中死亡率也有统计学意义的显著降低。创伤后阶段进行的手术显示抑肽酶组的死亡率较低。强调了休克治疗中时间因素的重要性以及抑肽酶在创伤性休克中的作用。
