[The pathophysiology of tourniquet shock].

In rabbits a tourniquet shock was produced by 4-hour unilateral ischemia of one hind leg. By measuring the tissue oxygen tension on the surface of the ischemically damaged muscle, the liver and kidney the regional rate of perfusion of these organs in the state of shock was investigated. Additionally morphological examinations of muscle, liver, kidney and heart were carried out. In therapeutic trials with a proteinase inhibitor (Trasylol), prednisolone and streptokinase, Trasylol proved to prolong the time of survival significantly.