Mestrovic J N
Fortschr Med. 1976 Mar 11;94(8):441-4.
Crohn's disease is characterised by its unknown etiology and pathogenesis, its many complications and its extraordinary disposition of recurrence. The perforation of the small intestine, or of the colon, obstruction and massive bleeding are severe complications, requiring immediate surgical attention. Frequently specific formation of fistulae is indicative of the first sign of the disease. A radical operative treatment--by present results (approximately 70% of cases)--is the method of choice. The tendency to extend surgical procedures to the chronic stage of the disease has been discussed in recent years. Complications observed in patients under study have also been analysed.
克罗恩病的特点是病因和发病机制不明、并发症众多且复发倾向异常。小肠或结肠穿孔、梗阻和大量出血是严重并发症，需要立即进行手术治疗。瘘管的特异性形成常常是该病的首发迹象。根据目前的结果（约70%的病例），根治性手术治疗是首选方法。近年来，已讨论了将手术程序扩展至疾病慢性阶段的趋势。还分析了研究中患者观察到的并发症。
