Barthod F, Patel J C
Service de chirurgie générale, Hôpital A. Paré, Boulogne sur Seine.
J Chir (Paris). 1993 Feb;130(2):90-6.
Crohn's disease (CD) is a chronic pan-enteric inflammatory disease of unknown etiology. Although treatment of CD of small intestine is at present principally medical, in the majority of cases surgical intervention is unavoidable, essentially to treat complications such as occlusion, intra- and/or extra-abdominal abscess, certain fistulae, intraperitoneal perforation, profuse hemorrhage and neoplastic degeneration. Surgery may also be indicated during acute episodes of corticotherapy resistant CD, and as a valid alternative to only partially effective long term corticoid treatment of an active chronic disease. Experience has shown that surgery should be as conservative as possible, "stricturoplasty" being the treatment of choice for stenotic lesions. Postoperative follow-up conditions have still to be formulated because of the marked variations in manifestations of recurrence of the disease.
克罗恩病(CD)是一种病因不明的慢性全肠道炎症性疾病。虽然目前小肠克罗恩病的治疗主要是药物治疗,但在大多数情况下,手术干预是不可避免的,主要用于治疗诸如肠梗阻、腹内和/或腹外脓肿、某些瘘管、腹腔穿孔、大量出血和肿瘤性退变等并发症。在对皮质类固醇治疗耐药的克罗恩病急性发作期间,以及作为对活动性慢性病长期皮质类固醇治疗仅部分有效的有效替代方案时,也可能需要进行手术。经验表明,手术应尽可能保守,“狭窄成形术”是狭窄性病变的首选治疗方法。由于该病复发表现差异很大,术后随访条件仍有待制定。