Parisi G, Gobbini A R, Vedovini G, Castro R, Campanella G, Biagi P
Minerva Med. 2000 Jan-Feb;91(1-2):31-8.
A brief review of Takayasu's Arteritis (TA), a chronic granulomatous arteritis that mainly affects the aorta and its major branches, is made. The various ethiopathogenetic mechanisms which may give origin to the vascular damage and its pathologic pattern are described. TA is a more widespread disease than previously stated, it is not exclusive of young women of Japanese origin but it is actually present worldwide irrespective of age and with variegated patterns of clinical and angiographic presentation. However, two main forms may be identified: the Japanese form in which prevails the aortic arch involvement and the Indian form in which vasculitis is present in abdominal aorta and its branches (above all the renal arteries) with an upright extension to the thoracic aorta and a protean clinical picture with a more systemic spectrum. The new clinical and angiographic criteria for TA definition are reviewed and stressed.
对高安动脉炎(TA)进行简要综述,这是一种主要累及主动脉及其主要分支的慢性肉芽肿性动脉炎。描述了可能导致血管损伤及其病理模式的各种病因发病机制。TA是一种比先前所述更为广泛的疾病,它并非日本裔年轻女性所特有,实际上在世界各地都有,不分年龄,临床和血管造影表现多样。然而,可以识别出两种主要形式:以主动脉弓受累为主的日本型和腹主动脉及其分支(尤其是肾动脉)出现血管炎并向上延伸至胸主动脉且临床表现多样、具有更广泛全身症状谱的印度型。对TA定义的新临床和血管造影标准进行了综述并强调。