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高安氏病和颞动脉炎。

Takayasu's disease and temporal arteritis.

作者信息

Giordano J M

机构信息

Department of Surgery, George Washington University Medical Center, Washington, DC 20037, USA.

出版信息

Semin Vasc Surg. 1995 Dec;8(4):335-41.

PMID:8775889
Abstract

Takayasu's disease and temporal arteritis are similar entities that predominantly affect women. There are significant differences. Takayasu's disease is a rare disorder that affects the aorta and its main branches in young women, whereas temporal arteritis is a common disorder that affects small- to medium-sized arteries of elderly women. The pathology of Takayasu's disease extends to all three arterial layers, whereas in temporal arteritis the disease affects the media and adventitia less, with giant cells more prominent. The diagnosis of Takayasu's disease depends on clinical presentation and characteristics of angiography, whereas temporal arteritis is diagnosed by clinical findings and arterial biopsy. Steroids are only palliative in Takayasu's disease with a high incidence of recurrences, whereas steroids in temporal arteritis are curative with good long-term results. Finally, surgery plays an important role in the care of patients with Takayasu's disease, but is used infrequently in those patients diagnosed with temporal arteritis.

摘要

高安氏病和颞动脉炎是主要影响女性的相似病症。但它们存在显著差异。高安氏病是一种罕见疾病,主要影响年轻女性的主动脉及其主要分支,而颞动脉炎是一种常见疾病,主要影响老年女性的中小动脉。高安氏病的病理累及动脉的所有三层,而颞动脉炎对中膜和外膜的影响较小,巨细胞更为突出。高安氏病的诊断取决于临床表现和血管造影特征,而颞动脉炎则通过临床症状和动脉活检来诊断。类固醇药物对高安氏病仅起到缓解作用,复发率较高,而对颞动脉炎而言,类固醇药物具有治愈效果,长期效果良好。最后,手术在高安氏病患者的治疗中发挥重要作用,但在被诊断为颞动脉炎的患者中很少使用。

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