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咪喹莫特的临床应用

Imiquimod in clinical practice.

作者信息

Edwards L

机构信息

Southeast Vulvar Clinic, Charlotte, North Carolina, USA.

出版信息

J Am Acad Dermatol. 2000 Jul;43(1 Pt 2):S12-7. doi: 10.1067/mjd.2000.107806.

DOI:10.1067/mjd.2000.107806
PMID:10861102
Abstract

Numerous clinical trials have shown topical imiquimod (Aldara) to be effective and safe for the treatment of anogenital warts. In addition, the recurrence rate appears to be lower than those reported for many standard therapies of genital warts. Clinical experience with this medication since its availability 2 years ago has shown that it is important in the therapy of this disease. However, it is not the ideal treatment in all cases, and the advantages and disadvantages in individual patients must be considered. In addition, the antiviral and antiproliferative effects of imiquimod, as well as early reports, indicate that this medication may prove useful in the treatment of other skin diseases, including some nongenital warts and molluscum contagiosum.

摘要

大量临床试验表明,局部使用咪喹莫特(艾达乐)治疗肛门生殖器疣有效且安全。此外,其复发率似乎低于许多已报道的生殖器疣标准疗法。自该药物两年前面市以来的临床经验表明,它在这种疾病的治疗中很重要。然而,它并非在所有情况下都是理想的治疗方法,必须考虑个体患者的优缺点。此外,咪喹莫特的抗病毒和抗增殖作用以及早期报告表明,这种药物可能在治疗其他皮肤病方面有用,包括一些非生殖器疣和传染性软疣。

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Imiquimod in clinical practice.咪喹莫特的临床应用
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2
Topical immunomodulators for the treatment of external genital warts, cutaneous warts and molluscum contagiosum.用于治疗外生殖器疣、皮肤疣和传染性软疣的局部免疫调节剂。
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A study on the use of imiquimod for the treatment of genital molluscum contagiosum and genital warts in female patients.咪喹莫特治疗女性患者生殖器传染性软疣和尖锐湿疣的研究。
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