Bakir F, Al-Khalidi A, Clarkson T W, Greenwood R
Bull World Health Organ. 1976;53 Suppl(Suppl):87-92.
Twenty-six patients suffering from methylmercury poisoning were treated by different therapeutic regimes. Seven received penicillamine or N-acetyl-d-L-penicillamine, 10 were treated with dimercaprol sulfonate and 9, who could not be treated, were given a placebo and were used as controls. Penicillamine, N-acetyl-d-L-penicillamine, and dimercaprol sulfonate reduced the blood level of mercury and increased its urinary excretion. No appreciable clinical improvement was noticed among the severe or very severe cases, while mild or moderate cases improved clinically irrespective of the treatment given.
26例甲基汞中毒患者接受了不同的治疗方案。7例接受青霉胺或N-乙酰-d-青霉胺治疗，10例接受二巯丙磺钠治疗，9例因无法接受治疗而给予安慰剂作为对照。青霉胺、N-乙酰-d-青霉胺和二巯丙磺钠降低了血液中的汞水平并增加了其尿排泄量。在重度或极重度病例中未观察到明显的临床改善，而轻度或中度病例无论接受何种治疗临床症状均有改善。
