[科特迪瓦肠道病原体的分离：大肠杆菌O157:H7和肠聚集性大肠杆菌]
[Isolation of enteric pathogeic agents in Côte d'Ivoire: Escherichia coli O157:H7 and enteroaggregative E. coli].
作者信息
Dadié A, Karou T, Adom N, Kétté A, Dosso M
机构信息
Institut Pasteur, Laboratoire de bactériologie-virologie, Abidjan, Côte d'Ivoire.
出版信息
Bull Soc Pathol Exot. 2000 Apr;93(2):95-6.
New pathogens including Escherichia coli O157:H7 have emerged and spread world-wide as the most important cause of foodborne infections. We established a prospective study in Abidjan from 1996 to 1999 to determine the prevalence of Shiga-toxin producing E. coli (STEC) in our environment. Two O157 strains were found. One (EA47) O157:H7 was isolated from chicken and the other (EH144) O157:HNM from human diarrhoeal stool specimens. Both O157 strains carried stx2, eae, and UidA genes, but not e-hly one. Four other pathogenic E. coli were isolated, including three enteroaggregative E. coli (EAggEC) and one isolate which expresses a cytolethal distending toxin gene (cdtB). This is the first report of Shiga-toxin producing E. coli (STEC) in Côte d'Ivoire. Given its low prevalence (0.8%), E. Coli does not appear to be a public health problem in Côte d'Ivoire.
包括大肠杆菌O157:H7在内的新病原体已出现并在全球传播，成为食源性感染的最重要病因。1996年至1999年，我们在阿比让开展了一项前瞻性研究，以确定环境中产生志贺毒素的大肠杆菌（STEC）的流行情况。发现了两株O157菌株。一株（EA47）O157:H7从鸡肉中分离得到，另一株（EH144）O157:HNM从人类腹泻粪便标本中分离得到。两株O157菌株均携带stx2、eae和UidA基因，但不携带e-hly基因。还分离出另外四种致病性大肠杆菌，包括三株肠聚集性大肠杆菌（EAggEC）和一株表达细胞致死膨胀毒素基因（cdtB）的分离株。这是科特迪瓦首次关于产生志贺毒素的大肠杆菌（STEC）的报告。鉴于其低流行率（0.8%），大肠杆菌在科特迪瓦似乎不是一个公共卫生问题。
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