Roques F, Nashef S A, Michel P, Pinna Pintor P, David M, Baudet E
Service de Chirurgie Cardio-vasculaire, CHU de Fort de France, 97200 Fort de France, Martinique, France.
Eur J Cardiothorac Surg. 2000 Jul;18(1):27-30. doi: 10.1016/s1010-7940(00)00417-6.
Because of national epidemiological differences in adult heart surgery in Europe, the effectiveness and desirability of a pan-European score for the assessment of quality of surgical care remains controversial. We assessed the predictive value of EuroSCORE in national subsets of the EuroSCORE database.
The EuroSCORE development data set was divided into national subsets of which those with 500 or more patients were selected for analysis. The Hosmer-Lemeshow goodness-of-fit test was applied to assess the calibration of the EuroSCORE model on individual national samples and the areas under the receiver operating characteristic (ROC) curve were measured to analyse the EuroSCORE discriminative power on individual death prediction.
There were 18676 patients in the six largest national samples: Germany, United Kingdom, Spain, Finland, France and Italy (mean: 3113 patients; range: Finland 1266 to France 4507). Major differences were observed in national distribution of procedures: coronary artery bypass grafting accounted for 77.7% of procedures in Finland but only 46.2% in Spain. The EuroSCORE model goodness-of-fit was satisfactory in all countries (P-value overall: 0.4; UK: 0.34; Finland: 0.87; no values less than 0.05). Areas under ROC curves were 0.81 in Germany, 0.79 in the UK, 0.74 in Spain, 0.87 in Finland, 0.82 in France and 0.82 in Italy.
Despite epidemiological differences between European countries, the discriminative power of EuroSCORE was good in Spain and excellent in all other countries. The system, developed from a merged European database, can therefore be used to assess improvement in quality of care achieved by surgeons and institutions as well as for international European comparison in adult heart surgery.
由于欧洲各国成人心脏手术的流行病学存在差异,用于评估手术护理质量的泛欧洲评分的有效性和适用性仍存在争议。我们在欧洲心脏手术风险评估系统(EuroSCORE)数据库的各国子集中评估了EuroSCORE的预测价值。
将EuroSCORE开发数据集划分为各国子集,选择其中患者数量不少于500例的子集进行分析。采用Hosmer-Lemeshow拟合优度检验评估EuroSCORE模型在各个国家样本中的校准情况,并测量受试者工作特征(ROC)曲线下面积,以分析EuroSCORE在个体死亡预测方面的鉴别能力。
六个最大的国家样本(德国、英国、西班牙、芬兰、法国和意大利)共有18676例患者(平均:3113例患者;范围:芬兰1266例至法国4507例)。各国手术分布存在重大差异:冠状动脉搭桥术在芬兰的手术中占77.7%,而在西班牙仅占46.2%。EuroSCORE模型的拟合优度在所有国家均令人满意(总体P值:0.4;英国:0.34;芬兰:0.87;无值小于0.05)。德国的ROC曲线下面积为0.81,英国为0.79,西班牙为0.74,芬兰为0.87,法国为0.82,意大利为0.82。
尽管欧洲各国存在流行病学差异,但EuroSCORE在西班牙的鉴别能力良好,在所有其他国家表现出色。因此,该系统基于合并的欧洲数据库开发,可用于评估外科医生和机构在护理质量方面的改进,以及欧洲成人心脏手术的国际比较。