Katz R J
Psychopharmacology (Berl). 1979 Mar 14;61(1):39-41. doi: 10.1007/BF00426808.
A receptor selective agonist and antagonist of inhibition-mediating dopamine receptors (type II receptors) produced significant and dose-related alterations in bar-pressing for intracranial reward. Receptor inhibition by piribedil increased responding for reward while receptor activation by 3,4-dihydroxyphenylamino-2-imidazoline reduced responding. Inhibition-mediating receptors may therefore play a role opposite to classic excitation-mediating receptors in controlling reward.
一种抑制性介导多巴胺受体（II型受体）的受体选择性激动剂和拮抗剂，对颅内奖赏的压杆行为产生了显著且与剂量相关的改变。piribedil对该受体的抑制增加了对奖赏的反应，而3,4-二羟基苯氨基-2-咪唑啉对该受体的激活则减少了反应。因此，抑制性介导受体在控制奖赏方面可能发挥与经典兴奋性介导受体相反的作用。
