Dobardzić R, Dobardzić A
University of Kuwait and Farwania Hospital, Kuwait.
Med Arh. 2000;54(1):13-6.
To assess the occurrence frequency of bacterial pathogens at the Surgical Wards, Casualty and Outpatient Department (OP) of major Kuwaiti hospital and to compare their antimicrobial susceptibility patterns.
The Automicrobic System (bioMerieux-Vitek) with respective ready-to-use cards were used for identification of isolates and their susceptibility testing. Vitek DataTrac software automatically tabulated the occurrence rate of pathogens or their antimicrobial susceptibility percentage--for defined periods of time and specified patient locations.
The most common organisms for surgical inpatient isolates were E. coli, S. aureus, K. pneumoniae and P. aeruginosa; but for blood culture and sputum, by far, the most common were coagulase-negative staphylococci and K. pneumoniae, respectively. E. coli from wounds were less susceptible (for 12-26%) to ampicillin, co-amoxiclave, cephalothin and cefuroxime than surgical inpatient, OP or casualty E. coli isolates. Cephalothin and piperacillin susceptibility rates of K. pneumoniae of surgical in- and outpatients were twice higher than that of respective E. coli isolates.
The occurrence frequency of bacterial pathogens were dependent on the surgical services. Overall, antimicrobial susceptibility rates were high for different surgical subcategories, especially for casualty and inpatients. The lowest susceptibility rate showed the wound isolates versus beta-lactams, except third generation cephalosporins.
评估科威特主要医院外科病房、急诊室和门诊部细菌病原体的发生频率，并比较它们的抗菌药敏模式。
使用带有各自即用型卡片的自动微生物系统（生物梅里埃-维泰克）对分离株进行鉴定及其药敏试验。维泰克数据追踪软件会自动列出病原体的发生率或其在特定时间段和指定患者位置的抗菌药敏百分比。
外科住院患者分离株中最常见的微生物是大肠杆菌、金黄色葡萄球菌、肺炎克雷伯菌和铜绿假单胞菌；但就血培养和痰液而言，到目前为止，最常见的分别是凝固酶阴性葡萄球菌和肺炎克雷伯菌。伤口分离出的大肠杆菌对氨苄西林、阿莫西林克拉维酸、头孢噻吩和头孢呋辛的敏感性低于外科住院患者、门诊部或急诊室分离出的大肠杆菌（12%-26%）。外科住院和门诊患者肺炎克雷伯菌对头孢噻吩和哌拉西林的敏感率是相应大肠杆菌分离株的两倍。
细菌病原体的发生频率取决于外科服务。总体而言，不同外科亚类的抗菌药敏率较高，尤其是急诊室和住院患者。除第三代头孢菌素外，伤口分离株对β-内酰胺类药物的药敏率最低。
