Bernet F, Denimal J
Psychopharmacology (Berl). 1979 Mar 22;61(2):191-5. doi: 10.1007/BF00426735.
It has been shown in male rats of two albino strains, Wistar and Sprague-Dawley, that differences in emotional reactivity were related to physiological differences (Bernet and Denimal, 1978). Particularly the resting heart rate was slower in the more emotionally reactive rats. It has been suggested that emotional reactivity is linked with a certain neurovegetative balance. This possibility was investigated in twelve rats of each strain by means of differential blockade of the autonomic nervous system by atropine and propranolol. The heart rate response of the emotionally reactive strain to propranolol was statistically smaller than that of the non reactive strain. On the other hand, the heart rate increase resulting from atropine treatment was more elevated in the same rats. The calculated sympathetic and parasympathetic tones (as % of intrinsic heart rate) were 8% and 30% respectively in the reactive rats. However, both of the tones were 14% in the non reactive rats. In conclusion, the high defecating rats in the open-field exhibit a lower sympathetic tone linked with a higher parasympathetic tone.
在两种白化病品系的雄性大鼠（Wistar和Sprague-Dawley）中已表明，情绪反应性的差异与生理差异有关（伯内特和德尼马尔，1978年）。特别是情绪反应性较强的大鼠静息心率较慢。有人提出情绪反应性与某种神经植物性平衡有关。通过阿托品和普萘洛尔对自主神经系统进行差异阻断，对每个品系的12只大鼠进行了此项可能性的研究。情绪反应性品系对普萘洛尔的心率反应在统计学上小于非反应性品系。另一方面，同一批大鼠中阿托品治疗引起的心率升高更为明显。反应性大鼠计算出的交感神经和副交感神经张力（占固有心率的百分比）分别为8%和30%。然而，非反应性大鼠的两种张力均为14%。总之，旷场试验中排便频繁的大鼠表现出较低的交感神经张力和较高的副交感神经张力。
